抗癌和免疫抑制剂已广泛应用于临床。其副作用如消化道反应、皮疹、脱毛、骨髓抑制、继发感染、过敏性休克及对心、肺、肝、肾和中枢神经系统的毒性作用等,已为人所熟悉和注意。随着肿瘤治疗的改进,病人生存期的延长;组织器官移植研究的广泛开展和免疫抑制剂的大量应用,各国学者对其诱发合并症的病理变化、发生机理、影响因素、临床特点及早期发现等进行了深入的观察和研究。复习这些资料将有助于对这类药物的合理应用及合并症的诊断和鉴别。 Anti-cancer and immunosuppressive agents have been widely used clinically. Its side effects such as digestive tract reaction, skin rash, hair removal, bone marrow suppression, secondary infection, anaphylactic shock, and toxic effects on heart, lung, liver, kidney, and central nervous system are well known and noted. With the improvement of tumor treatment, prolongation of patient survival, extensive development of tissue and organ transplantation studies, and large-scale application of immunosuppressants, the pathological changes, mechanisms, influencing factors, clinical features, and early detection of complications induced by scholars in various countries Such as in-depth observation and research. Reviewing these data will help in the rational use of such drugs and the diagnosis and identification of comorbidities.