论文部分内容阅读
乳腺癌常用的化疗方案目前仍以CAF和CMF方案为主,且常与内分泌疗法或放疗联合应用,以作为复发性或转移性乳腺癌的标准一线治疗方案.然而,研究发现相当一部分病人对这些治疗产生不应性或耐药性.为此,作者采用由氨甲喋呤(MTX)、5-氟脲嘧啶(5-Fu)、甲酰四氢叶酸(LV)和顺铂(CDDP)组成的MFL-P方案治疗21例曾作过放化疗等治疗的复发性或转移性乳腺癌,以观察该方案的治疗效果.
Breast cancer commonly used chemotherapy regimens are still dominated by CAF and CMF regimens, and are often used in combination with endocrine therapy or radiotherapy as a standard first-line treatment option for recurrent or metastatic breast cancer. However, studies have found that a significant proportion of patients have Treatment produces refractoriness or drug resistance. To this end, the authors used MFLs consisting of methotrexate (MTX), 5-fluorouracil (5-Fu), leucovorin (LV), and cisplatin (CDDP). P regimen treatment in 21 cases had been treated with radiotherapy and chemotherapy, such as recurrent or metastatic breast cancer, in order to observe the treatment effect of the program.