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目的为增加不能手术切除肝癌病人的治疗机会，完善肝癌冷冻治疗术。方法总结1994年6月至1997年12月我肝癌研究所采用LCS-2000型冷冻机治疗原发性肝癌51例，继发性肝癌6例的治疗体会。所有病例均为晚期肝癌。冷冻术中B超引导下确定肿瘤及冷冻针位置并监测冷冻范围。冷冻深度达-198℃，冰球超过肿瘤组织1cm。结果术中27例未输血。术后均有发烧，平均恢复正常时间9天。术后SGPT较术前显著升高（P＜0．01），平均恢复术前水平时间9．4天。BUN手术前后无显著区别。术后继发出血3例，肝肾功能不全各1例。随访1年生存率61．5％，二年生存率38．2％。结论深度冷冻术是治疗肝癌的一种有效方法。继发出血及肝肾功能不全是其主要并发症。
The purpose is to increase the chance of treatment for liver cancer patients who cannot be surgically treated, and improve the treatment of liver cancer cryotherapy. Methods From June 1994 to December 1997, the Liver Cancer Institute of China used the LCS-2000 freezer to treat primary liver cancer in 51 patients and secondary liver cancer in 6 patients. All cases were advanced liver cancer. The location of tumors and frozen needles was determined under the guidance of B-ultrasonography during cryosurgery and the extent of cryosurgery was monitored. The cryogenic depth reached -198°C and the ice ball exceeded the tumor tissue by 1cm. Results 27 cases were not transfused during surgery. There was a fever after the operation, and the average normal time was 9 days. Postoperative SGPT was significantly higher than before surgery (P<0.01), and the average recovery time was 9.4 days before surgery. There was no significant difference between before and after BUN surgery. Subsequent to the operation, 3 cases of blood were transmitted and 1 case of liver and renal insufficiency. Follow-up 1 year survival rate 61.5%, two-year survival rate 38.2%. Conclusion Deep cryotherapy is an effective method for the treatment of liver cancer. Following blood and liver and kidney insufficiency are its major complications.