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选择符合ＷＨＯ诊断标准的不稳定型心绞痛（ＵＡ）５２例，随机分为治疗组３２例，对照组２０例。治疗组先静滴肝素５０～１００ｍｇ／ｄ３～５天，停肝素前２天服华法令２．２５～９ｍｇ／ｄ．对照组静滴低分子右旋糖酐２５０ｍｌ加复方丹参２０ｍｌ／ｄ，疗程２周。两组均给予阿司匹林、消心痛、心痛定、倍他乐克，治疗组长期口服华法令。观察３～１８个月。结果：治疗组有效率９６．８％，对照组有效率８５．０％。治疗组心绞痛缓解时间较对照组明显缩短，凝血酶原时间较对照组明显延长，血液粘稠度较对照组也有较好的改善。揭示：长期口服华法令可逆转血液的高凝状态，预防或减少急性心肌梗塞的发生。
Fifty-two cases of unstable angina pectoris (UA) who meet WHO diagnostic criteria were randomly divided into treatment group (n = 32) and control group (n = 20). The treatment group first intravenous infusion of heparin 50 ~ 100mg / d3 ~ 5 days, 2 days before stopping heparin taking warfarin 2.25 ~ 9mg / d. Control group intravenous infusion of low molecular weight dextran 250ml plus compound Salvia 20ml / d, treatment for 2 weeks. Both groups were given aspirin, anti-heart pain, painkillers, Betaloc, the treatment group long-term oral warfarin. Observation of 3 to 18 months. Results: The effective rate was 96.8% in the treatment group and 85.0% in the control group. The treatment group angina pectoris time was significantly shorter than the control group, prothrombin time significantly longer than the control group, blood viscosity than the control group also better improved. Revealed: Long-term oral warfarin can reverse the blood hypercoagulability, prevent or reduce the incidence of acute myocardial infarction.