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为了研究椎基底动脉供血障碍时耳蜗血流的变化及其调节作用，用激光多普勒血流计观察了３１只豚鼠椎基底动脉部分阻断时耳蜗血流及血压变化。其中５只豚鼠观察了罂粟碱及颈上神经节切除对内耳缺血的影响，发现惟基底动脉部分阻断时耳蜗血流明显减少（Ｐ＜０．００１），血压升高（Ｐ＜０．０５）。颈上神经节切除５分钟，耳蜗血流及血压无明显变化文Ｐ＞０．０５）。罂粟碱应用后２０分钟，耳蜗血流明显改善（Ｐ＜０．０００１）。颈上神经节切除后再次给予罂粟碱，耳蜗血流亦有增加，但较单纯应用罂粟碱时低。耳蜗血流与血压两者间无相关性。提示椎基底动脉供血障碍时耳蜗血流减少比较持续而稳定，罂粟碱明显改善豚鼠耳蜗血流说明肌源性调节的作用，而交感神经对内耳血流调节作用微弱。
Cochlear blood flow and blood pressure were observed in 31 guinea pig vertebrobasilar arteries in order to study the changes of cochlear blood flow and its regulation in vertebrobasilar artery disorders. Five of the guinea pigs observed the effects of papaverine and suprasternal ganglionectomy on ischemia in the inner ear. The results showed that cochlear blood flow decreased (P <0.001) and blood pressure increased (P <0. 05). 5 minutes after excision of the superior cervical ganglion, there was no significant change in cochlear blood flow and blood pressure (P> 0.05). Cochlear blood flow was significantly improved 20 minutes after papaverine administration (P <0.0001). After the excision of the superior cervical ganglion, papaverine was given again, and the blood flow to the cochlea was also increased, but lower than that of papaverine alone. There was no correlation between cochlear blood flow and blood pressure. Tip vertebrobasilar artery disorders when cochlear blood flow reduction is relatively constant and stable, papaverine significantly improved cochlear blood flow in guinea pig myogenic regulation role, and sympathetic to the inner ear blood flow regulation weak.