建立绵羊感染细粒棘球蚴 (Echinococcusgranulosus,E.g)疾病模型 ,应用于包虫病的防治研究。将羊源 E.g原头节经腹腔及颈内静脉接种 2 4只绵羊 ,依据感染率、囊肿体积与分布等指标 ,建立绵羊感染 E.g疾病模型。结果显示感染率为 91.6 % ,囊肿平均体积 (13.92± 2 .5 3) cm3。多数囊肿分布于腹腔或附着于腹壁、肠系膜、大网膜等 ,部分侵入肝脏和肺脏。本模型制备方法简单 ,感染率高 ,对包虫病的防治研究具有重要的实用价值。 A sheep model of Echinococcus granulosus (E.g) infection was established to study the prevention and treatment of hydatid disease. 24 sheep were inoculated intraperitoneally and intra-jugular vein with E.glural head of sheep, and the E.g disease model of sheep was established according to the infection rate, cyst volume and distribution. The results showed that the infection rate was 91.6%, the average volume of cysts (13.92 ± 2. .5 3) cm3. Most cysts distributed in the abdominal cavity or attached to the abdominal wall, mesentery, omentum, etc., part of the invasion of the liver and lungs. The preparation method of the model is simple and the infection rate is high, which has important practical value for the prevention and treatment of hydatid disease.