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1977年我们在浙江省海宁县利用线网细胞采集器擦取直肠粘膜细胞作涂片镜检,在86,673例涂片中发现78例核异质细胞,10例腺癌细胞,并经病理切片证实,两者符合率100％。在涂片中还发现各类寄生虫卵,如血吸虫卵2,576例,钩虫卵887例,蛔虫卵14,759例。通过大量工作实践,我们认为用线网细胞采集器擦取直肠粘膜细胞涂片镜检,作大肠癌诊断,方法安全、可靠,简便,易行,阳性率高,可作为大肠癌普查的手段之一,对肠道寄生虫病的诊断也有一定帮助。文中并对直肠粘膜各类脱落细胞的特征作了较详细的描述,强调了肠粘膜细胞易于退变,特别是肿胀性退变的特点。国内类似资料尚较少见。
In 1977, we used a wire network cell harvester to wipe rectal mucosal cells for smear examination in Haining County, Zhejiang Province. 78 cases of nuclear heterogeneous cells and 10 cases of adenocarcinoma cells were found in 86,673 smears and confirmed by pathological section. The coincidence rate is 100%. Various parasite eggs were also found in the smear, such as 2,576 schistosome eggs, 887 hookworm eggs and 14,759 roundworm eggs. Through a large number of work practices, we believe that the use of wire mesh cell harvester to wipe rectal mucosa cell smear microscopy for colorectal cancer diagnosis, method is safe, reliable, simple, easy, high positive rate, can be used as a means of colon cancer screening First, the diagnosis of intestinal parasites is also helpful. In this paper, the features of exfoliated cells of the rectal mucosa were described in detail, emphasizing that the intestinal mucosal cells are prone to degeneration, especially the characteristics of swelling degeneration. Similar domestic data are still rare.