阿克拉霉素(aclacinomycin,aclaru-bicin,ACM)是一类蒽环类抗肿瘤抗生素,主要抗肿瘤活性成分有 ACM-A 和 ACM-B,其中 ACM-A 作用稍强于 ACM-B。ACM与以往常用的蒽环类,如阿霉素和红霉素相比,主要特点是心脏毒性很小,无明显致突变和致癌作用,且有较强的抗肿瘤活性。因此,ACM 被认为是更有效的蒽环抗肿瘤药 Acclarinomycin (aclaru-bicin, ACM) is a class of anthracycline antitumor antibiotics. The main antitumor active ingredients are ACM-A and ACM-B, of which ACM-A is slightly stronger than ACM-B. Compared with the commonly used anthracyclines, such as doxorubicin and erythromycin, ACM is characterized by its minimal cardiotoxicity, no obvious mutagenicity and carcinogenesis, and strong antitumor activity. Therefore, ACM is considered to be a more effective antitumor anticancer agent