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目的:分析果洛地区藏族世居住院患者血脂的分布特征,为治疗与预防提供相应理论依据。方法:将2012年1月—2013年12月收治入院果洛藏族自治州人民医院(海拔3 700m)内科的高海拔地区2 763例藏族世居患者做为研究对象,随机依照年龄分为(18~29)岁、(30~39)岁、(40~49)岁,(50~59)岁和≥60岁组,分析血清总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)与极低密度脂蛋白胆固醇(VLDL-C)等五项指标的分布情况。结果:血脂五项指标值(50~59)岁年龄段患者TC、TG的异常发生率显著高于其他组患者(P<0.001)。男性血脂水平>女性(P<0.001)。与高脂血症相伴随的常见疾病依次为脂肪肝、原发性高血压、冠心病、糖尿病、脑梗死。结论:果洛地区藏族世居住院患者血脂水平普遍高于平原地区,TC、TG异常与上述心脑血管疾病、脂肪肝及糖尿病密切相关。
Objective: To analyze the distribution characteristics of blood lipids in in-patients in inhabited areas in Guoluo area and to provide the corresponding theoretical basis for treatment and prevention. Methods: A total of 2 763 Tibetan patients living in high altitude at the People’s Hospital of Guoluo Tibetan Autonomous Prefecture (3 700 m above sea level) admitted from January 2012 to December 2013 were randomly divided into two groups according to their ages (18 ~ (TC), triglyceride (TG), high-density lipoprotein cholesterol (LDL-C) in patients with chronic hepatitis B (29-29), (30-39), (40-49), (50-59) (HDL-C), low-density lipoprotein cholesterol (LDL-C) and very low density lipoprotein cholesterol (VLDL-C). Results: The abnormal rates of TC and TG in the five-index blood lipid (50-59) age group were significantly higher than those in other groups (P <0.001). Male blood lipid levels were> female (P <0.001). Common diseases associated with hyperlipidemia followed by fatty liver, essential hypertension, coronary heart disease, diabetes, cerebral infarction. Conclusion: The prevalence of blood lipids in hospitalized in-patients in Guoluo area is generally higher than that in plain areas. The abnormalities of TC and TG are closely related to the cardiovascular and cerebrovascular diseases, fatty liver and diabetes mentioned above.