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目的了解中国不同地区、不同感染途径人类免疫缺陷病毒(HIV)合并丙型肝炎病毒(HCV)感染情况。方法调查既往有偿采供血173人、静脉吸毒89人和性途径194人的HIV感染者人口学、感染途径、献血/卖血史、吸毒史、同性性行为史、婚外性行为史及检测HCV-IgG抗体。结果总HCV-IgG抗体阳性率63.24%;既往有偿采供血、静脉吸毒和性途径HIV感染者HCV-IgG阳性率分别为95.40%,98.88%,18.04%;合并HCV感染的危险因素为既往有偿采供血(OR=89.84,95%CI=40.31～200.24)和静脉吸毒感染(OR=363.72,95%CI=48.90～∞);河南省和新疆维吾尔族自治区性途径合并HCV感染率分别为19.81%,25%,明显高于辽宁省的2.94%(P<0.01)。结论HIV感染者总HCV-IgG阳性率显著高于我国一般人群。经性接触感染HIV者的HCV感染率显著低于经静脉吸毒和经血途径,经吸毒感染HIV和经既往有偿采供血感染HIV是感染HIV的危险因素。经性感染HIV由于地域和性伴不同,HCV合并感染率差异有统计学意义。
Objective To understand the infection status of human immunodeficiency virus (HIV) and hepatitis C virus (HCV) in different regions of China. METHODS: We investigated the demographics, routes of infection, blood donation / seizure history, history of drug abuse, history of same-sex sexual behavior, history of extra-marital sexually transmitted diseases and detection of HCV in HIV-infected patients with 173 blood donors, 89 drug users and 194 HIV patients. -IgG antibody. Results The positive rate of HCV-IgG was 63.24%. The positive rates of HCV-IgG were 95.40%, 98.88% and 18.04%, respectively. The risk factors for HCV infection were as follows: (OR = 89.84, 95% CI = 40.31-200.24) and intravenous drug use (OR = 363.72, 95% CI 48.90 ~ ∞). The prevalence of HCV infection in Henan province and Xinjiang Uygur Autonomous Region was 19.81% 25%, which was significantly higher than that of Liaoning Province (2.94%, P <0.01). Conclusion The positive rate of HCV-IgG in HIV-infected patients was significantly higher than that of the general population in our country. The HCV infection rate in HIV-infected persons was significantly lower than that of trans-intravenous drug use and menstrual route. HIV infection through drug use and HIV infection through past paid blood supply were the risk factors for HIV infection. Sexually Transmitted Infections Because of differences in geographical and sexual partners, the prevalence of HCV co-infection was statistically significant.