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放射性骨髓再障时浆细胞数明显增加,往往占剩余细胞的大多数。该现象并非种属特性,因所有实验动物都有,在原子弹受难者也存在。目前尚未完全了解浆细胞数是绝对或相对增高,放射性综合症过程中其累积的动态变化如何,以及在电离辐射引起免疫抑制条件下该现象的意义是什么? 实验用两性杂种狗62只,用最低绝对致死剂量的~(60)Coγ射线照射。于照后不同时间用通电法杀死动物,每时间点(30分钟,3、6、8小时,1、3、7、10、11和12天)用5只狗。取胸骨、肋骨、脊柱和酪前上脊的骨髓检查。各骨用甲醛固定;脱钙后25%EDTA
Radioactive bone marrow cells significantly increased the number of plasma cells, often accounted for most of the remaining cells. This phenomenon is not a species characteristic, because all experimental animals have, also exist in the atomic bomb victims. It is not yet fully understood whether the plasma cell number is absolute or relative increase. What is the significance of this phenomenon under the conditions of ionizing radiation-induced immunosuppression? The experiment used 62 breeders dogs with The lowest absolute lethal dose of ~ (60) Co γ-ray irradiation. Animals were killed by electroporation at different times after irradiation. Five dogs were used at each time point (30 minutes, 3, 6, 8 hours, 1, 3, 7, 10, 11 and 12 days). Bone marrow examination of the sternum, ribs, spine and anterior superior bracing. Each bone was fixed with formaldehyde; 25% EDTA after decalcification