论文部分内容阅读
目的探讨影响腹膜透析患者发生心血管钙化的相关危险因素。方法收集50例接受腹膜透析治疗患者的临床资料(主要为可能导致心血管钙化的资料),包括年龄、性别、体质量指数(BMI)、体表面积(BSA)、血压、原发疾病、透析龄,血清钙、磷,糖、脂代谢水平,肾功能指标等,根据患者是否发生心血管钙化分为钙化组和非钙化组,比较两组患者以上的资料是否有差异,再将有组间差异的指标用Logistic回归分析筛选出可以用于预测腹膜透析患者发生心血管钙化的高危因素和保护因素。结果经评估,钙化组28例患者,非钙化组22例患者。经Logistic回归分析,年龄、透析龄、血清磷、残余肾功能与心血管钙化相关。结论高龄、高透析龄、高血清磷、低残余肾功能均是腹膜透析患者发生心血管钙化的重要危险因素。因此,临床上对于高龄、长期行腹膜透析治疗的患者应高度重视其钙磷平衡,及时采取干预措施保护患者的残余肾功能,以降低其心血管钙化的发生,同时预防心血管疾病的发生。
Objective To investigate the related risk factors affecting cardiovascular calcification in peritoneal dialysis patients. Methods The clinical data of 50 patients undergoing peritoneal dialysis (mainly data that may lead to cardiovascular calcification) including age, sex, body mass index (BMI), body surface area (BSA), blood pressure, primary disease, dialysis age , Serum calcium, phosphorus, sugar, lipid metabolism, renal function indicators, etc., according to whether patients with cardiovascular calcification were divided into calcification group and non-calcification group, comparing the two groups of patients above data are there any differences, and then there are differences between groups Logistic regression analysis was used to identify risk factors and protective factors that could be used to predict cardiovascular calcification in peritoneal dialysis patients. RESULTS: Twenty-eight patients in the calcified group and 22 in the non-calcified group were evaluated. Logistic regression analysis showed that age, dialysis age, serum phosphorus and residual renal function were related to cardiovascular calcification. Conclusion The elderly, high dialysis age, high serum phosphorus and low residual renal function are important risk factors of cardiovascular calcification in peritoneal dialysis patients. Therefore, clinically for elderly, long-term peritoneal dialysis patients should pay close attention to the balance of calcium and phosphorus, and timely interventions to protect patients with residual renal function, in order to reduce the occurrence of cardiovascular calcification, and prevent cardiovascular disease.