目的对2008-2010年3月娄底市手足口病疫情与检测结果进行分析,为娄底市手足口病防控措施提供依据。方法采用荧光定量PCR方法对所采标本进行检测,并对所检样品中EV71、CA16及其它肠道病毒所占比例和临床症状与2008、2009年所占比例和临床症状进行分析。结果今年该市EV71所占比例大幅上升,可能是今年该市手足口病疫情较严重的原因。结论今年娄底市手足口病流行较前二年形势更严峻,宜及时采取相应防控措施。 Objective To analyze the epidemic situation of HFMD in Loudi City from March 2008 to March 2010 and provide the basis for the prevention and control measures of HFMD in Loudi City. Methods Fluorescent quantitative PCR was used to detect the samples and the proportion and clinical symptoms of EV71, CA16 and other enteroviruses in the samples were analyzed. The proportion and clinical symptoms in 2008 and 2009 were analyzed. As a result, the proportion of EV71 in this city has risen sharply this year, which may be the reason that the epidemic of HFMD in this city is more serious this year. Conclusion This year, the epidemic situation of hand-foot-mouth disease in Loudi City is even more severe than in the previous two years. Corresponding prevention and control measures should be taken in time.