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目的探讨米非司酮与利凡诺用于疤痕子宫中期妊娠引产疗效及安全性。方法剖宫产疤痕子宫中期妊娠顿服米非司酮200 mg,24 h羊膜腔注射利凡诺100 mg引产33例作为观察组;入院后单用羊膜腔注射利凡诺100 mg引产28例作为对照组。观察用药后,宫颈成熟,宫缩到胎儿胎盘娩出时间,引产并发症。结果观察组用药后宫颈成熟度高于对照组(P<0.01);宫缩到胎儿胎盘娩出时间短于对照组(P<0.01);观察组引产成功率100%,对照组引产成功率96.5%。两组均常规行清官术,观察组清出残留胎盘胎膜少于对照组(P<0.05)。结论米非司酮诱导宫颈成熟,结合利凡诺羊膜腔注射引起官缩,两者相互协调,缩短产程,提高引产成功率,减少并发症发生。是一项安全、有效的引产方法。
Objective To investigate the efficacy and safety of mifepristone and rivanol in the induction of labor during mid-term pregnancy with scar. Methods cesarean section scar uterus midterm pregnancy Dayton mifepristone 200 mg, 24 h amniotic injection of rivanol 100 mg induction of labor in 33 cases as the observation group; admission to the amniotic cavity after injection of rivanol 100 mg induction of labor as a Control group. Observed after treatment, cervical ripening, contractions to the fetal placenta delivery time, induced labor complications. Results The cervix maturation rate in the observation group was higher than that in the control group (P <0.01); the time from uterine contraction to fetal placenta delivery was shorter than that in the control group (P <0.01); the success rate of induction of labor was 100% in the observation group and 96.5% . Both groups routinely clean up the arteries, the observation group was less residual placenta membranes than the control group (P <0.05). Conclusion Mifepristone induces cervical ripening, combined with rivanol amniotic cavity injection caused by official contraction, the two coordinated with each other, shorten the labor process, improve the success rate of induction of labor and reduce the incidence of complications. Is a safe and effective method of induction of labor.