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本文探讨了天麻浸膏的抗惊及镇痛作用,同时也测定了天麻浸膏的急性毒性. 1.抗惊实验用戊四氮作快速尾静脉注射使小白鼠产生全身阵挛性惊厥,而预先腹腔注射天麻浸膏具有明显的对抗戊四氮阵挛性惊厥的作用,其峯作用时间为30—60分钟,此后作用逐渐减弱,于240分钟时,作用约减弱一半. 2.镇痛实验用吕富华等修改的Reinhard.de.Beer Grewal法,结果证明天麻浸膏无明显镇痛作用. 3.LD_(50)测定表明天麻浸膏的毒性甚低.
This article discusses the anti-seizure and analgesic effects of Gastrodia extract, and also determines the acute toxicity of Gastrodia extract. 1. Anticonvulsive test using pentylenetetrazole for rapid tail vein injection to produce mice with systemic clonic convulsions, and Pre-intraperitoneal injection of Rhizoma Gastrodiae has obvious anti-pentatetrazole spasmolytic convulsions, with a peak acting time of 30-60 minutes, after which the effect gradually weakens. At 240 minutes, the effect is attenuated by about half. 2. Analgesic test Reinhard.de.Beer Grewal method modified by Lü Fuhua et al. proved that Tianma extract had no obvious analgesic effect. 3. LD_(50) showed that the toxicity of Gastrodia extract was very low.