本文观察了给予维生素C(Vit C)后小鼠肾脏及原代人胚肾上皮细胞的血卟啉光动力学效应,Vit C可以部分地保护碱性磷酸酶、细胞色素氧化酶和琥珀酸脱氢酶,降低血卟啉光动力学对这些酶的抑制作用,但不能减轻细胞结构的破坏,也不能延缓肾组织坏死出现的时间。实验结果表明;自由基可能是血卟啉光动力学中的一种作用形式,但主要作用形式可能是由于单态氧的作用。 The photodynamic effects of hematoporphyrins in mouse kidney and primary human embryonic kidney epithelial cells after vitamin C administration were observed. Vitamin C can partially protect alkaline phosphatase, cytochrome oxidase, and succinic acid. Hydrogenase reduces the inhibitory effect of hemodynamics of hematoporphyrin on these enzymes, but it can not reduce the damage of cell structure, nor can it delay the time of renal tissue necrosis. The experimental results show that free radicals may be a form of photodynamics in hematoporphyrins, but the main mode of action may be due to the role of singlet oxygen.