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为研究探讨血管内皮细胞生长因子 (VEGF)在原发性肝细胞癌 (HCC)的表达及其临床病理意义 ,我们应用免疫组织化学 (S P法 )对 34例HCC中VEGF的表达作了研究。结果 :HCC中VEGF的表达较对照组织显著增高。VEGF的表达与HCC的病理分级程度相关 ,与肿瘤是否发生侵袭及转移行为可能有关。结论 :VEGF在HCC发展中可能有一定的促进作用 ,VEGF与HCC的病理分级程度相关 ,还可能是估计HCC侵袭及转移能力的一个标志
To study the expression of vascular endothelial growth factor (VEGF) in primary hepatocellular carcinoma (HCC) and its clinicopathological significance, we used immunohistochemistry (S P method) to study the expression of VEGF in 34 cases of HCC. Results : The expression of VEGF in HCC was significantly higher than that in control tissue. The expression of VEGF is related to the degree of pathological grade of HCC and may be related to whether the tumor has invaded and metastatic behavior. Conclusion: VEGF may play a role in promoting the development of HCC. VEGF is associated with the degree of pathological grade of HCC, and may also be a marker for assessing the invasion and metastasis of HCC.