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目的观察藏药六味木香丸抗炎、镇痛作用。方法采用热板致小鼠疼痛法、乙酸致小鼠扭体反应法及甲醛致小鼠疼痛法研究六味木香丸的镇痛作用;采用对二甲苯致小鼠耳廓肿胀和小鼠棉球肉芽肿试验研究六味木香丸的抗炎作用。结果六味木香丸高、中剂量能明显抑制乙酸及甲醛致小鼠疼痛;高剂量能减轻二甲苯致小鼠耳廓肿胀度及小鼠棉球肉芽肿干重。结论六味木香丸具有良好的抗炎镇痛作用。
Objective To observe the anti-inflammatory and analgesic effect of Tibetan medicine Liuwei Muxiang Pills. Methods The analgesic effect of Liuwei Juxiang Pill was studied by hot plate induced pain in mice, acetic acid induced writhing reaction in mice and formaldehyde induced pain in mice. Granulomatous Experimental Study on the Anti - inflammatory Effect of Liuwei Juxian Pills. Results High and medium doses of Liuwei Quxiang Wan could significantly inhibit the pain induced by acetic acid and formaldehyde in mice. High doses could reduce the swelling of auricles and the dry weight of cotton granuloma in mice induced by xylene. Conclusion Liuwei Muxiang Wan has good anti-inflammatory and analgesic effects.