Summary: ISO9000 quality management system (ISO9000QMS) emphasize on the customer-orient-ed, managers leadership and all staffs joining, adopt the process method and system management,spread the taking facts as a basis to make decision and improve consistently, and establish win-win relation with the suppliers. So, the digital hospital can adopt the ISO9000QMS. In order to establish the ISO9000QMS, the digital hospital should: (1) Design integrally, including analyzing the opera tion procedure, clarifying the job duties, setting up the spreading team and setting the quality policy and objectives: (2) Learning the ISO9000 quality standards; (3) Drawing up the documents, include-ing the quality manual, program files and operation guiding files; (4) Training according the docu ments; (5) Executing the quality standard, including the service quality auditing, quality record au-diting and quality system auditing; (6) Improving continually. With the establishment of ISO900QMS, the digital hospital can appraise more accurately, analyze quality matters statistically and avoid the interference of artificial factors.