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目的:建立HPLC法标定头孢呋辛对照品含量的不确定度评定方法。方法:建立数学模型,对含量测定过程中各影响因素进行分析评估。结果:通过计算各变量的不确定度,合成不确定度,最终得出测定结果的扩展不确定度。结论:该评定方法适用于HPLC法标定头孢呋辛对照品含量的不确定度评定。
Objective: To establish an HPLC method for the determination of the content of cefuroxime in the evaluation of uncertainty. Methods: To establish a mathematical model to analyze and evaluate the influential factors in the determination of content. Results: By calculating the uncertainty of each variable, the uncertainty was synthesized and finally the extended uncertainty of the measurement results was obtained. Conclusion: This method is suitable for evaluating the uncertainty of the content of cefuroxime axetil in HPLC.