药物相互作用的概念及临床意义药物相互作用是指在同时使用两种或两种以上药物时,所伴随出现的继发性反应。这种反应的结果,可使药效增强或减弱,进而出现有利作用或有害作用。如将减少心血排出量的药物与降低外周血管阻力的药物合并应用,可使降压效果增强,而羧苯磺胺与青霉素合用则可提高后者的抗 The concept and clinical significance of drug interactions Drug interactions refer to the secondary reactions that accompany the simultaneous use of two or more drugs. As a result of this reaction, the efficacy can be enhanced or diminished, which in turn can have a beneficial or detrimental effect. If the combination of drugs that reduce cardiovascular output and drugs that reduce peripheral vascular resistance enhances antihypertensive effects, the combination of sulfonatine and penicillin increases the latter