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选择T2DM 1级亲属糖耐量正常者83人为实验组,三代无糖尿病家族史健康83人为对照组,测血清胆固醇(TC)、甘油三脂(TG)、高密度脂蛋白(HDL)。低密度脂蛋白胆固醇(LDL-C)依据公式:LDL-C=TC-TG/5-HDL。用SPSS13.5软件配对t检验。结果:两组相比TC、HDL、LDL-C:P>0.05无显著差异,TG:P<0.05有显著差异。结论:2型糖尿病1级亲属糖耐量正常者与三代无糖尿病家系相比血清TG升高。
Eighty-three subjects with T2DM grade 1 relatives with normal glucose tolerance were selected as the experimental group. 83 healthy family members with no family history of diabetes mellitus were selected as the control group. Serum cholesterol (TC), triglyceride (TG) and high density lipoprotein (HDL) were measured. Low-density lipoprotein cholesterol (LDL-C) is based on the formula: LDL-C = TC-TG / 5-HDL. Paired t-test with SPSS13.5 software. Results: Compared with TC, HDL, LDL-C: no significant difference between the two groups, TG: P <0.05 significant difference. Conclusions: Serum TG is elevated in patients with type 1 diabetes who have normal glucose tolerance compared with those in the third generation without diabetes.