以细胞杂交为主的细胞工程学近年来取得了令人嘱目的进展。在核质关系、基因定位、基因转移、杂交瘤单克隆抗体以及肿瘤细胞去恶性化等诸多领域均日益显示出其广阔的应用前景。十几年来,各国学者运用细胞工程学的一些主要技术方法,对肿瘤细胞去恶性 Cell engineering based on cell hybridization has made remarkable progress in recent years. In the nuclear-mass relationship, gene mapping, gene transfer, hybridoma monoclonal antibodies, and degeneration of tumor cells, many areas have increasingly demonstrated its broad application prospects. Over the past decade, scholars from various countries have used some of the main technical methods of cell engineering to eliminate malignant tumor cells.