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通过对大量放线菌属进行抗菌活性系统筛选,于1948年发现了金霉素(氯四环素)。提取金霉素的新菌种命名为金色链丝菌,因其菌落呈金黄色。虽然刚发现了氯霉素,但当时普遍使用的抗菌素仅是青霉素及链霉素。金霉素及氯霉素有两大优点:可以口服及具有广谱的
Chlortetracycline (chlortetracycline) was discovered in 1948 by screening a large number of actinomycetes for antibacterial activity. A new strain of chlortetracycline named golden streptococcus, because of its golden colonies. Although chloramphenicol has just been found, antibiotics commonly used at that time were only penicillin and streptomycin. Chlortetracycline and chloramphenicol have two major advantages: can be oral and have a broad spectrum