甲状腺毒症不仅可使原已存在的心脏病加重,而且其本身亦可引起心脏病。这一概念是由 Levine等提出的,他们根据临床观察认识到甲状腺毒症作为单独的或主要因素可导致心脏增大、心房颤动或充血性心衰。甲状腺毒症时总血容量增加使心脏产生高容量负荷,后者使心脏作功增加,最终导致心脏肥厚。甲状腺毒症时虽然收缩力及舒张松弛速率均增加, Thyrotoxicosis not only aggravates the existing heart disease, but also causes heart disease by itself. This concept was proposed by Levine et al. Who, based on clinical observations, recognized that thyrotoxicosis as a single or major factor can lead to heart enlargement, atrial fibrillation, or congestive heart failure. The increase in total blood volume during thyrotoxicosis causes the heart to produce a high volume load, which increases the work of the heart and eventually leads to cardiac hypertrophy. Although thyrotoxicosis systolic and diastolic relaxation rate increased,