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目的研究MK、VEGF-A在原发性输卵管腺癌组织中的表达,并探讨其临床意义。方法应用S-P法研究42例原发性输卵管腺癌标本中MK、VEGF-A的表达情况。采用SPSS13.0统计软件包进行统计学分析。结果 MK及VEGF-A在原发性输卵管腺癌中为高表达,与正常输卵管组织之间差异有统计学意义(P<0.01),且与肿瘤临床分期及病理类型相关(P<0.05)。结论 MK、VEGF-A的表达上调可能对原发性输卵管腺癌的发生发展中起重要作用。
Objective To study the expression of MK and VEGF-A in primary fallopian tube adenocarcinoma and to explore its clinical significance. Methods S-P method was used to study the expression of MK and VEGF-A in 42 cases of primary fallopian tube adenocarcinoma. SPSS13.0 statistical software package for statistical analysis. Results MK and VEGF-A were overexpressed in primary fallopian tube adenocarcinoma. The difference was statistically significant (P <0.01) with normal fallopian tube tubulointerstitial tumor (P <0.01), and correlated with clinical stage and pathological type (P <0.05). Conclusion The up-regulation of MK and VEGF-A may play an important role in the occurrence and development of primary fallopian tube adenocarcinoma.