肠道假性梗阻是一种临床病种,它具有肠梗阻的症状和体征,但无肠腔内外梗阻的过程,其范围可局限或广泛。急性型多见于慢性疾患或老年病人,多有致病因素;而慢性型常找不到致病原因。许多情况可引起肠道假性梗阻,在诊断慢性原发性肠道假性梗阻综合征时应予考虑。【巨结肠症】在新生儿的发生率约为1/5000,男:女为9∶1,恒定的表现为出生头一个月就便秘,但25％病人可有腹泻。有些到老年时才出现症状。钡剂灌肠可以显示一具有神经节的扩张肠曲与无神经节的萎陷肠曲之间的转变区,直肠压力测定未见尖峰活力。直肠活检发现乙酰胆碱脂酶活性增加和神经束增多。诊断巨结肠症的必备条件是粘膜下层和肌层神经丛内缺乏神经节细胞。Kottmeier 等报道62例小儿巨结肠症,其中2/3证实无神经节,从症状和体征不易与功能 Pseudo-intestinal obstruction is a clinical disease, it has the symptoms and signs of intestinal obstruction, but no intestinal obstruction inside and outside the process, the scope can be limited or extensive. Acute type more common in chronic diseases or elderly patients, and more risk factors; and often can not find the cause of chronic disease. Many cases can cause intestinal pseudo-obstruction, in the diagnosis of chronic primary intestinal obstruction syndrome should be considered. Hirschsprung’s disease occurs in about 1 in 5000 in newborns and 9 to 1 in men and women. Consistent performance is constipation in the first month of life, but 25% of patients have diarrhea. Some symptoms to old age. Barium enema can show a transition zone between the dilated bowel with ganglion and the detrusor intestinal ganglia without ganglion, and no peak vitality was detected in the rectal pressure test. Rectal biopsies showed increased acetylcholinesterase activity and increased nerve bundles. The prerequisite for diagnosis of megacolon disease is the lack of ganglion cells in the submucosa and myenteric plexus. Kottmeier et al reported 62 cases of Hirschsprung’s disease in children, of which 2/3 confirmed no ganglion, from the symptoms and signs difficult and function