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本文用放射免疫方法测定了妊娠高血压综合征妇女血浆中前列环素与血栓素稳定代谢产物的含量,结果发现,妊高征妇女血浆中6-Keto-PGF_(1α)的含量明显低于正常妊娠组;而TxB_2的含量高于正常妊娠组。提示前列环素与血栓素的变化与妊高征的病理生理变化有关。
The content of prostacyclin and thromboxane in plasma of pregnant women with pregnancy induced hypertension was measured by radioimmunoassay. The results showed that the content of 6-Keto-PGF_ (1α) in women with PIH was significantly lower than normal Pregnancy group; while the content of TxB_2 was higher than that of normal pregnancy group. Prompt prostacyclin and thromboxane change and pregnancy-induced hypertension pathophysiological changes.