先天性无眼球是胚胎早期视窝及视泡形成发生障碍所致。同胞兄弟先天性无眼球罕见。现报道两例。例1:男,生后3天,于1982年3月30日出生,第三胎,足月顺产。全身检查未见异常。眼部检查:右眼的上下眼睑缘连在一起,无睑裂;左眼的上下眼睑缘除在靠鼻侧处有一个1毫米大小的裂隙外,其余部分均连在 Congenital absence of the eyeball is early embryo neovascularization and optic disc formation due to obstacles. Siblings congenital non-eye rare. Two cases are reported now. Example 1: Male, 3 days after birth, was born on March 30, 1982, the third child, full-term birth. No abnormalities in the whole body examination. Eye examination: the upper and lower right eyelid eyelid together, no palpebral fissure; left eye upper and lower eyelid except at the nasal side there is a 1 mm size of the gap, the rest are even in the