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用放射性惰性气体测定组织血流量开始于1955年,由 Lassen 与 Munck 报告用~(85)氪(~(85)Kr)作脑血流量测定。以后在其他脏器也广泛应用,在肝脏也进行着基础和临床研究。放射性惰性气体测定肝血流量的原理是向肝脏注入脂溶性放射性惰性气体后,依血液—肝组织分配系数,该气体容易在肝组织中扩散,并流往血液中去,而流到肝静脉去的放射性惰性气体又可通过肺把95%以上从呼气排出,几乎不回肝脏再循环。也就是在肝
Tissue blood flow measurements using radioactive inert gas began in 1955 and were reported by Lassen and Munck as ~ (85) krypton (~ (85) Kr) for cerebral blood flow measurements. After the other organs are also widely used in the liver is also undergoing basic and clinical research. Radioactive inert gas Determination of liver blood flow principle is to inject fat-soluble radioactive inert gas into the liver, according to the blood - liver tissue partition coefficient, the gas easily spread in the liver tissue, and to the blood flow to go to the hepatic vein go The radioactive inert gas can be more than 95% through the lungs exhaled exhaled, almost no back to the liver to recycle. That is, in the liver