论文部分内容阅读
锂盐是治疗躁郁症的常用药,它与多种肾脏并发症有关。但引起肾病综合征者较少。作者报告一例糖尿病患者持续用锂盐11年导致的肾病综合征。 病例,男,56岁。因意识模糊和共济失调入院。11年前被诊断为躁郁症,给予锂盐每日1.5g,每月血锂监测在治疗量范围。8年前患成人型糖尿病,用胰岛素治疗。一年前尿检查无蛋白。10天前渐起头痛、意识模糊,口齿不清和震颤。无外伤或感觉异常史。除多尿外,无提示肾病的病史。入院体查:血压220/110mmHg,眼底轻度视网膜病变,神经系统检查主要发现震颤,构音困难,肢体共济失调,轻度意识模糊,但无局灶性体征。实验室检
Lithium salts are commonly used drugs for the treatment of bipolar disorder and are associated with a variety of kidney complications. However, fewer people cause nephrotic syndrome. The authors report a case of nephrotic syndrome in patients with diabetes who have been on lithium for 11 years. Case, male, 56 years old. Admitted to hospital due to confusion and ataxia. 11 years ago was diagnosed with bipolar disorder, given lithium daily 1.5g, monthly blood lithium monitoring in the therapeutic range. 8 years ago with adult diabetes, insulin treatment. Urinalysis a year ago without protein. 10 days ago gradually headache, confusion, speechless and tremor. No history of trauma or sensory abnormalities. In addition to polyuria, no history of renal disease prompted. Admission physical examination: blood pressure 220 / 110mmHg, retinal mild retinopathy, nervous system examination found mainly tremor, dysarthria, limb ataxia, mild confusion, but no focal signs. Laboratory test