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消炎痛(Indomethacin,Indocin)是吲哚衍生物,属于一种非甾体抗炎解热镇痛药,用于炎性疼痛如风湿性及类风湿性关节炎、骨关节炎,强直性脊柱炎,急性疼痛及癌性发热。近年来,随着对其抑制前列腺素合成酶并具有抗凝和促进纤维蛋白溶解作用的研究发掘,使消炎痛在临床上得到上较以往更为广泛的应用,现简要综述如下:一、用于抗感染性休克邓(?)飞等对暴发型休克型流脑患儿12例临床观察,常规治疗加消炎痛0.5～1.0mg1kg,入院后1～2小时肌注,能迅速改善休克的低血压和低氧分压,逆转休克的血流动力学异常,提高患儿的存活率。
Indomethacin (Indocin) is an indole derivative belonging to a non-steroidal anti-inflammatory antipyretic analgesic for inflammatory pain such as rheumatoid and rheumatoid arthritis, osteoarthritis, ankylosing spondylitis , Acute pain and cancerous fever. In recent years, with its inhibition of prostaglandin synthase with anticoagulant and fibrinolysis to explore the role of indomethacin clinically obtained more widely used than in the past, are briefly summarized as follows: First, the use of In the anti-infective shock Deng (?) Fly and other 12 cases of fulminant shock-type meningitis in children with routine treatment plus indomethacin 0.5 ~ 1.0mg1kg, 1 to 2 hours after admission intramuscular injection, can quickly improve the shock low Blood pressure and hypoxic partial pressure, hemodynamic reversal of shock abnormalities, improve the survival rate of children.