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目的:分析恶性肿瘤患者Rh血型表型的分布特点,并与正常对照组进行比较,查找恶性肿瘤与Rh血型表型相关性。方法:对120例恶性肿瘤患者(患者组)及100例正常健康人群(对照组)进行Rh血型表型测定,对其表型分布进行统计分析,采用χ2检验和相对危险度OR值来估计相对危险性。结果:恶性肿瘤患者组与对照组Rh血型表型CcDEe分布之间的差异有统计学意义(χ2=4.51,P<0.05)。恶性肿瘤患者组Rh血型表型分布从高到低分别是CcDEe54例(45.00%),CCDee39例(32.50%),CcDee14例(11.67%),ccDEE9例(7.50%),ccDEe3例(2.50%),CCDEe1例(0.83%);对照组Rh血型表型分布从高到低分别是CCDee47例(47.00%),CcDEe32例(32.00%),ccDEE9例(9.00%),CcDee6例(6.00%),ccDEe5例(5.00%),CCDEe1例(1.00%);结论:恶性肿瘤的发生与Rh血型表型的分布有关,CcDEe(OR=1.82)、CcDee(OR=2.07)表型发病率明显高于其他表型。
OBJECTIVE: To analyze the distribution of Rh blood type phenotype in patients with malignant tumors and to compare with the normal control group to find out the correlation between the phenotype of malignant tumor and Rh blood group. Methods: Rh blood type phenotype was determined in 120 patients with malignant tumor (patient group) and 100 normal healthy people (control group), and their phenotype distribution was statistically analyzed. Chi-square test and relative odds ratio (OR) were used to estimate relative Dangerous. Results: There were significant differences in the distribution of Rhc phenotype CcDEe between malignant tumor patients and controls (χ2 = 4.51, P <0.05). The distribution of Rh blood type phenotypes in patients with malignant tumor was high (CcDEe54cases (45.00%), CCDee39cases (32.50%), CcDee14cases (11.67%), ccDEE9cases (7.50%) and ccDEe3cases (2.50% CCDEe1 (0.83%). The distribution of Rh blood type phenotype in control group were 47 cases of CCDee (47.00%), 32 cases of CCDe (32.00%), 9 cases of ccDEE (9.00%), 6 cases of CcDee (OR = 1.82) and CcDee (OR = 2.07) were significantly higher than those of other phenotypes (5.00%) and 1 case of CCDEe (1.00%). Conclusion: The incidence of malignant tumors was related to the distribution of Rh blood type phenotypes. .