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采用组织化学和免疫组织化学方法对胃肠道脾性肿瘤组织及肿瘤周围组织内分泌细胞进行了观察。结果表明:良性腺瘤有腺癌组织中存在内分泌细胞,许多肿瘤组织及胂瘤周围组织中可同时存在2种或2种以上的免疫活性内分泌细胞。这些内分泌细胞的存在可能对肿瘤的发生、发展以及在肿瘤免疫方面起到重要作用。本文研究的结果支持了内分泌细胞内胚层起源说。本试验结果还显示嗜银细胞和免疫活性5—羟色胺(irSer)细胞的分布存在着差异。
Histochemical and immunohistochemical methods were used to observe the endocrine cells of gastrointestinal spleen tumor tissues and surrounding tissues of tumors. The results showed that there were endocrine cells in adenocarcinoma of benign adenoma. Two or more kinds of immunocompetent endocrine cells could coexist in many tumor tissues and surrounding tissues of tumor. The presence of these endocrine cells may play an important role in the occurrence and development of tumors and in tumor immunity. The results of this study support the endogenous cell endoderm. The results of this experiment also showed a difference in the distribution of erythrophilic cells and immunoreactive serotonin (irSer) cells.