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目的评价131I-SPECT/CT断层融合显像对分化型甲状腺癌的临床应用价值。方法比较90例分化型甲状腺癌患者131I治疗后同时进行131I-WBS和131I-SPECT/CT断层融合显像(100次)与单纯进行131I-WBS(80次)时的病灶诊断的优缺点。所有结果均通过病理、其他影像检查和临床随访予以证实。结果同时进行131I-WBS和131I-SPECT/CT断层融合显像80例次,均得到局部病变的三维图像,可以直观病变形态、体积、摄取程度,准确病变定位,并了解与周围组织的毗邻关系;只行单纯131I-WBS全身显像的100例次能明确判断病变部位的病例只有42例。两种显像方法检出的病例数差异显著(χ2=28.34,P<0.01)。结论 131I-SPECT/CT断层融合显像弥补了单纯131I-WBS全身显像存在平面显像的局限性,对提高DTC诊断正确率、指导治疗方案的调整具有重要影响,将在DTC的诊治上发挥更大作用。
Objective To evaluate the clinical value of 131I-SPECT / CT fusion imaging in differentiated thyroid cancer. Methods The advantages and disadvantages of 131I-WBS, 131I-SPECT / CT fusion imaging (100 times) and 131I-WBS (80 times) diagnosis of 131I-WBS (80 times) in 131 cases of differentiated thyroid cancer patients were compared. All results were confirmed by pathology, other imaging and clinical follow-up. Results Both 131I-WBS and 131I-SPECT / CT fusion imaging were performed in 80 cases at the same time. The three-dimensional images of the local lesion were obtained. The morphological changes, the volume, the degree of the lesion, the location of the lesion, and the adjacent relationship with the surrounding tissues ; Only simple 131I-WBS whole body imaging 100 cases can clearly determine the lesion site only 42 cases. There was significant difference between the two imaging methods (χ2 = 28.34, P <0.01). Conclusions 131I-SPECT / CT fusion imaging can make up for the limitations of planar imaging in 131I-WBS whole body imaging and has an important influence on improving the diagnosis accuracy of DTC and guiding the adjustment of treatment plan. It will play an important role in the diagnosis and treatment of DTC Greater effect.