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目的:对血清降钙素原(PCT)、C反应蛋白(CRP)在鉴别肺癌患者发热原因的价值评价分析,为临床工作提供参考依据。方法:选取2012年9月1日-2014年6月1日间住院的确诊为肺癌、在住院期间伴有发热的患者100例作为研究对象,将其按照发热原因分成:感染性发热组、肿瘤性发热组、非感染性发热组。对各组PCT和CRP等各项指标监测,并对监测结果进行对比分析。结果:经统计,感染性发热组PCT、CRP检测阳性率较其他两组显著升高(P<0.05),治疗后PCT与CRP水平明显降低(P<0.05);肿瘤性发热组PCT阳性率与非感染性炎性发热组比较,差异具有统计学意义(P<0.05);PCT对发热患者感染性发热诊断的敏感性、特异性均在80%以上。结论:在肺癌患者发热原因鉴别中,PCT与CRP检测的临床意义重大,并且PCT的敏感度和特异性良好,临床应对其给予足够的重视。
Objective: To evaluate the value of serum procalcitonin (PCT) and C-reactive protein (CRP) in differentiating the causes of fever in patients with lung cancer and provide reference for clinical work. Methods: A total of 100 hospitalized patients diagnosed as lung cancer during hospitalization from September 1, 2012 to June 1, 2014 were enrolled in this study. The patients were divided into fever group, infectious fever group, Sexual fever group, non-infectious fever group. Each group of PCT and CRP indicators such as monitoring, and monitoring results were compared. Results: The positive rates of PCT and CRP in infectious fever group were significantly higher than those in other two groups (P <0.05), and PCT and CRP levels were significantly lower after treatment (P <0.05). PCT positive rate and Non-infectious inflammatory fever group, the difference was statistically significant (P <0.05); PCT fever in patients with fever diagnostic sensitivity, specificity of more than 80%. Conclusion: In the identification of causes of fever in patients with lung cancer, the clinical significance of detection of PCT and CRP is significant, and the sensitivity and specificity of PCT are good, and should be paid enough attention in clinical practice.