目的了解毕节市2004-2013年甲型病毒性肝炎的流行特征,为制定防控策略提供依据。方法根据传染病报告信息管理系统数据,对2004-2013年毕节市甲肝疫情进行描述流行病学分析。结果毕节市2004-2013年累计报告甲肝病例6 394例,年均发病率为9.46/10万。高发县为威宁、金沙、黔西,3个县报告病例数占全市总病例数的66.94%。除流行年份有春季、夏秋季发病高峰外,平常年份无明显季节性发病高峰。近50%的病例为<15岁儿童,病例主要为学生、农民和散居儿童,三者占总病例数的86.48%。2004-2013年共发生甲肝突发公共卫生事件5起,报告病例1 936例,占总病例数的30.28%,是导致毕节市甲肝发病率周期性波动及季节性变化的主要原因。结论近年来,毕节市甲肝发病率虽然已控制在较低水平,但仍要警惕暴发疫情的发生。必须继续抓好甲肝疫苗常规接种,加大入学入托查验接种证工作力度,提高疫情监测敏感性,及时发现和处置聚集性病例。 Objective To understand the epidemiological characteristics of hepatitis A virus in Bijie City from 2004 to 2013 and provide the basis for the development of prevention and control strategies. Methods Based on the data of infectious disease reporting information management system, the epidemiological analysis of hepatitis A in Bijie City from 2004 to 2013 was conducted. Results A total of 6 394 hepatitis A cases were reported in 2004-2013 in Bijie City, with an average annual incidence of 9.46 / 100 000. High incidence of Weining, Sands, Qianxi, three counties reported the number of cases accounted for 66.94% of the total number of the city’s case. In addition to the prevalence of the spring, summer peak incidence, the normal season no significant seasonal peak. Nearly 50% of cases are children <15 years of age, with the majority of cases being students, farmers and children living in diaspora, accounting for 86.48% of the total number of cases. A total of 5 public health emergencies of hepatitis A were reported in 2004-2013, accounting for 1 936 cases, accounting for 30.28% of the total number of cases, leading to cyclical fluctuations and seasonal changes in the incidence of hepatitis A in Bijie City. Conclusion Although the incidence of hepatitis A in Bijie has been controlled at a relatively low level in recent years, it is still necessary to guard against the outbreak of the outbreak. We must continue to routine hepatitis A vaccination, increase admission to check the vaccination card work to improve the sensitivity of the epidemic monitoring, timely detection and disposal of aggregated cases.