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目的探讨睡眠呼吸暂停综合征（ＳＡＳ）患者体位及肥胖因素引起的肺功能改变与夜间低氧血症的关系。方法选择确诊为ＳＡＳ患者３４例，分别于坐位和仰卧位检查肺功能和血气分析，整夜多导睡眠仪监测。肺功能、血气指标和理想体重％（ＩＢＷ％）分别与呼吸暂停指数（ＡＩ）、＜９０％Ｔ（ＳａＯ２低于９０％时间占总睡眠时间百分比）进行相关分析。结果患者由坐位改为仰卧位，ＰａＯ２、肺活量（ＶＣ％）、补呼气量（ＥＲＶ）、功能残气量（ＦＲＣ％）、残气容积（ＲＶ％）、肺总量（ＴＬＣ％）均出现有统计学意义的降低。ＡＩ与仰卧位ＶＣ％、ＴＬＣ％呈正相关。＜９０％Ｔ与坐位ＰａＯ２、ＥＲＶ呈负相关。ＩＢＷ％与坐、仰卧位ＶＣ％和ＥＲＶ呈负相关，与坐位ＦＲＣ呈负相关。ＩＢＷ％与＜９０％Ｔ呈正相关。结论伴有肥胖的ＯＳＡＳ患者，体位改变及肥胖因素影响患者肺功能，加重呼吸暂停时的低氧血症
Objective To investigate the relationship between lung function changes and nocturnal hypoxemia caused by body position and obesity in patients with sleep apnea syndrome (SAS). Methods 34 patients diagnosed as SAS were selected. Lung function and blood gas analysis were performed in sitting position and supine position, and overnight polysomnography was performed. Pulmonary function, blood gas index and% body weight (IBW%) were correlated with apnea index (AI), <90% T (SaO2 less than 90% of total sleep time). Results The patient changed from sitting position to supine position. PaO2, VC, ERV, FRC%, RV% and TLC% all appeared There is a statistically significant decrease. AI and supine position VC%, TLC% was positively correlated. <90% T was negatively correlated with seat PaO2 and ERV. IBW% was negatively correlated with sitting and supine VC% and ERV, and negatively correlated with seating FRC. IBW% was positively correlated with <90% T. Conclusion Obese patients with OSAS, postural changes and obesity factors affect lung function in patients with aggravating apnea hypoxemia