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一组分类为新的二氧化碳噬细胞菌属(Capnocy-tophaga(的变异细菌最近已引起重视。这些细菌是兼性厌氧性、嗜二氧化碳的梭形革兰氏阴性杆菌。作者报导了6例患恶性肿瘤伴粒细胞缺乏症患者,10次发生二氧化碳噬细胞菌脓毒症。该6例病人中女4例,男2例。年龄为2.5～41岁;其中5例小于16岁。2名儿童患急性粒细胞白血病。另3名儿童患急性淋巴细胞白血病。其余的一例成人患结肠腺癌。6例发生10次脓毒症时总共14次血培养阳性。在这10次发病时临床上均出现中毒症状,体温39～40℃。并观察到口腔粘膜溃疡和牙龈出血各8次。半数在菌血症发病期间还有溃疡性口炎和牙龈肥厚.极度的粒细胞缺乏是最重要的实验室发现,在脓毒症时白细胞计数平均值1373/μl,范围200～4,000/μl;血涂片中均未见有成熟粒细胞.其中一例出现原始细胞危象的急性粒细胞白血病患儿,白细胞71,000/μl,其中99%为原粒细胞。
A group of bacteria of the genus Capnocy-tophaga (mutants of bacteria recently identified as facultative anaerobic, carbon dioxide-depleted spindle-shaped Gram-negative bacilli.) The authors reported 6 patients Malignant tumor with agranulocytosis, 10 times the occurrence of carbon dioxide cell sepsis, the 6 cases of women in 4 cases, 2 males, aged 2.5 to 41 years of age; 5 were less than 16 years old .2 children Suffering from acute myeloid leukemia in the other three children suffering from acute lymphoblastic leukemia and the remaining one case of adult suffering from colon adenocarcinoma in 6 cases of 10 sepsis occurred when a total of 14 blood culture positive in the clinical incidence of these 10 were Symptoms of poisoning, body temperature 39 ~ 40 ° C and oral mucosal ulcers and bleeding gums were observed 8. Half of the time in the incidence of bacteremia there ulcerative stomatitis and gingival hypertrophy. Extreme agranulocytosis is the most important experiment Room found that in the sepsis when the average white blood cell count 1373 / μl, the range of 200 ~ 4,000 / μl; blood smears were not seen in mature granulocytes. One case of blast crisis of acute myeloid leukemia in children, WBC 71,000 / μl , Of which 99% of the original granulocyte.