神经母细胞瘤继发骨髓纤维化尚属罕见,最近我科经骨髓活检证实1例。患儿,女,6岁,因间断发热,皮肤出血点和全身骨骼疼痛4个月入院。发病后曾在当地县医院诊为“血小板减少性紫癜”,口服泼尼松一个月后,皮肤出血点消退,但发热不退,贫血加重。既往体健。查体T38℃,R26,P110,BP13.3/10.7kPa,满月 Neuroblastoma secondary to bone marrow fibrosis is still rare, recently confirmed by biopsy in 1 case. Child, female, 6 years old, admitted to hospital with intermittent fever, skin bleeds and generalized bone pain for 4 months. After the onset of a local county hospital diagnosed as “thrombocytopenic purpura”, a month after oral prednisone, skin bleeding subsided, but fever, refrained, anemia. Past physical health. Physical examination T38 ℃, R26, P110, BP13.3 / 10.7kPa, full moon