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目的：探讨钠钾镁钙葡萄糖注射液对创伤失血性休克兔血流动力学、血糖和酸碱平衡的影响。方法采用Lamson’s法制作创伤失血性休克兔模型。日本长耳大白兔32只随机均分为4组：正常对照（NC）组，生理盐水（NS）组，乳酸钠林格氏液（LR）组，钠钾镁钙葡萄糖注射液（SPMCG）组；在限制复苏期给予不同干预，在充分复苏期给予相同干预；于休克前即基础期（T1）、休克末（T2）、限制复苏期末（T3）、充分复苏期末（T4）各时间点采动脉血进行血气分析。结果输液各组平均动脉压（MAP）、心率（HR）、呼吸频率（RF）、动脉血二氧化碳分压（PaCO2）以及血糖组间比较差异无统计学意义（P>0.05）。经液体复苏后， SPMCG组实验动物的pH值、血乳酸（Lac）及碱剩余（BE）的改善效果明显好于NS组和LR组（P0.05）。结论对创伤失血性休克兔使用钠钾镁钙葡萄糖注射液进行液体复苏，血糖水平不会显著升高，且更有利于维持其酸碱平衡。“,”Objective To explore the effects of Sodium Potassium Magnesium, Calcium and Glucose Injection on hemodynamics, blood glucose and the acid-base balance in rabbits with traumatic hemorrhagic shock (THS). Methods We induced THS by Lamson’s method. We divided the rabbits into four groups (n=8):NC group, NS group, LR group and SPMCG group. Different interventions on limited resuscitation phase were performed respectively. The same interventions were performed on full resuscitation phase. The blood samples Were collected at pre-shock,post-shock,the end of limited resuscitation and full resuscitation for blood gas analysis. Results MAP, HR, RF, PaCO2 and the blood glucose in infusion groups there were no significant differences (P>0.05). After the fluid resuscitation, compared with NS group and LR group, pH, the blood lactate (Lac) and base excess (BE) in SPMCG group had been significantly improved (P0.05). Conclusion In the fluid resuscitation of traumatic hemorrhagic shock rabbits, compared with saline solution and lactated Ringer’s, sodium potassium magnesium calcium and glucose injection is more advantageous to maintain the acid-base balance.