胰腺癌是常见的恶性肿瘤,其发病率,国外报道9.6人/10万,国内0.61～3.8人/10万。胰腺癌的诊断和治疗中,存在3个主要问题:①早期诊断困难。②有时术中判定病变性质决定术式困难。③手术复杂,侵袭性大,并发症多,死亡率高。一、早期诊断胰腺癌早期,2cm以下小胰腺癌,多无症状,如有症状,也不明显,无特异性,出现明显症状多属较晚期不能切除,目前尚无理想的筛选方法发现早期胰腺癌。40岁以上,上腹部不适隐痛、食欲减退或体重减轻等症状,特别是治疗无效。呈进行性,如查不出其他原因,应进一步检查除外胰腺癌。 Pancreatic cancer is a common malignancy, and its incidence is reported by 9.6 people per 100 thousand in foreign countries and 0.61 to 3.8 persons per 100 thousand in China. There are three major problems in the diagnosis and treatment of pancreatic cancer: 1 Early diagnosis is difficult. 2 It is sometimes difficult to determine the nature of the lesion during intraoperative determination. 3 Surgery is complicated, invasive, complications are many, and mortality is high. First, early diagnosis of pancreatic cancer, small pancreatic cancer less than 2cm, more than asymptomatic, if symptoms, no obvious, no specificity, there are obvious symptoms are mostly unremovable late, there is no ideal screening method to find the early pancreas cancer. Over 40 years old, the upper abdominal discomfort, loss of appetite or weight loss and other symptoms, especially ineffective treatment. Progressive, if no other reasons can be found, further examination should be made for pancreatic cancer.