论文部分内容阅读
高效腺病毒介导的抗ｒａｓ核酶致肿瘤细胞逆转ＦｅｎｇＭ，ＣａｂｒｅｒａＧ，ＤｅｓｈａｎｅＪ，ｅｔａｌ．ＣａｎｃｅｒＲｅｓ１９９５；５５：２０２４～２０２８本文采用策略为消除显性癌基因的异常表达以达到根除靶肿瘤细胞。该作者曾证明用锤头状核酶在激活的Ｈ┐ｒ...
Efficient adenovirus-mediated anti-ras nuclease-induced tumor cell reversal of FengM,CabreraG,DeshaneJ,etal. CancerRes 1995;55:2024~2028 This article uses a strategy to eliminate aberrant expression of dominant oncogenes to achieve eradication of target tumor cells. The authors have demonstrated the use of hammerhead ribozymes in the activation of H┐r...