adw、ayw、adr和ayr是HBsAg 4个主要遗传亚型,亚型有着不同的地理分布。虽然临床和实验研究表明乙型肝炎病毒(HBV)自然感染或疫苗免疫后存在交叉保护作用,但对抗-a发生的动力学和抗体应答的持久性以及抗-d或抗-y的定性和定量关系所知甚少。作者对105名(男64人,女41人)平均 adw, ayw, adr and ayr are the four major genetic subtypes of HBsAg, subtypes have different geographical distribution. Although clinical and experimental studies indicate that there is a cross-protective effect after natural infection with hepatitis B virus (HBV) or vaccine immunization, the kinetics and persistence of antibody responses to anti-a and the qualitative and quantitative anti-d or anti-y Little is known about the relationship. The authors average 105 (64 males and 41 females)