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1988年4月至1990年12月,以碘油—抗癌剂混悬液及明胶海绵碎粒栓塞肝癌的供血动脉(Lp—TAE)治疗原发性肝癌178例,累积生存率(Cumulative Survival Rate)分别是一年67.97％和二年43.51％。认为LP—TAE是肝癌的最好姑息手段。如何进一步提高疗效使姑息变成治愈?作者对178例患者的肝动脉造影,CT扫描片,手术病理标本等资料进行了对比分析,认为碘油抗癌药物混悬液沉积不充分是病灶未能完全被消灭的关键。影响药物充分沉积的主要因素是:①肝癌乏病理血管;②药量不足;③癌灶内严重的动静脉分流;④没有用明胶海绵栓塞或栓塞不充分;⑤肝动脉外供血;⑥混悬液制作不良等。强调了首次LP—TAE的重要性。
From April 1988 to December 1990, 178 cases of hepatocellular carcinoma (Lp-TAE) were treated with lipiodol-anticancer agent suspension and gelatin sponge embolization of liver cancer. Cumulative Survival Rate (Cumulative Survival Rate) ) They are 67.97% a year and 43.51% a year. It is believed that LP-TAE is the best palliative treatment for liver cancer. How to further improve the curative effect of palliative treatment into a cure? The author of 178 cases of patients with hepatic arteriography, CT scans, surgical pathological specimens and other data were compared and analyzed, that iodized oil anti-cancer drug suspension is not sufficient deposition is the lesion failed The key to being completely eliminated. The main factors affecting the full deposition of drugs are: 1 liver cancer lacks pathological blood vessels; 2 insufficient drug dose; 3 severe arteriovenous shunt within the cancer foci; 4 no embolization or embolization with gelatin sponge; 5 extrahepatic artery blood supply; 6 suspension Poor fluid production. Emphasize the importance of the first LP-TAE.