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目的了解常州市30～59岁农村人群高脂血症的现患率,评价该地区高脂血症的流行现况。方法采用随机整群抽样方法,对常州市农村地区10 018名常住居民进行流行病学调查并测定血清总胆固醇(TC)、血甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)等指标,根据2000年第5次全国人口普查资料对现患率进行年龄标化。结果该人群高脂血症的现患率为32.3%,标化率为31.3%,男性现患率高于女性(χ2=35.76,P<0.01);随着年龄的增加,高TC、高TG现患率逐渐上升(χ2趋势=70.98,P<0.01及χ2趋势=15.44,P<0.01)。且高脂血症现患率随着体力劳动程度的加重而逐渐降低(χ2趋势=80.70,P<0.01)。体质指数(BMI)与TC、TG值呈正相关(r=0.19,P<0.01;r=0.28,P<0.01),但与HDL-C值呈负相关(r=-0.22,P<0.01);腰围值(WC)与TC、TG值之间也呈正相关(r=0.19,P<0.01;r=0.32,P<0.01),但与HDL-C值也呈负相关(r=-0.26,P<0.01)。结论常州市30～59岁农村人群高脂血症现患率较高,并且有随年龄增加而增加的趋势;肥胖与TC、TG值均呈正相关,与HDL-C值呈负相关,证实肥胖可导致血脂升高,需要在该地区加强健康教育,倡导健康的生活方式,提倡合理的膳食结构,从而控制和预防高脂血症的发生。
Objective To understand the prevalence of hyperlipidemia in rural population aged 30-59 in Changzhou and to evaluate the prevalence of hyperlipidemia in this area. Methods A total of 10 018 permanent residents in rural areas of Changzhou were investigated by random sampling method and the levels of serum total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C) And other indicators, according to the 2000 fifth national census data on the prevalence of age-standardized. Results The prevalence of hyperlipidemia in this population was 32.3% and the standardization rate was 31.3%. The prevalence rate of male was higher than that of female (χ2 = 35.76, P <0.01). With the increase of age, the prevalence of high TC and high TG (Χ2 trend = 70.98, P <0.01 and χ2 trend = 15.44, P <0.01). The prevalence of hyperlipidemia gradually decreased with the increase of manual labor (χ2 trend = 80.70, P <0.01). Body mass index (BMI) was positively correlated with TC and TG (r = 0.19, P <0.01; r = 0.28, P <0.01) There was also a positive correlation between WC and TG values (r = 0.19, P <0.01; r = 0.32, P <0.01), but also negatively correlated with HDL- <0.01). Conclusion The prevalence of hyperlipidemia in rural population aged 30-59 years in Changzhou City is high and there is a trend of increasing with age. Obesity is positively correlated with TC and TG, and negatively correlated with HDL-C, which confirms that obesity can be Leading to increased blood lipids, the need to strengthen health education in the region, promote a healthy lifestyle, promote a reasonable diet to control and prevent the occurrence of hyperlipidemia.