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目的探讨老年高血压患者的平均脉压(ABPP)与左心室肥厚的关系。方法对180例老年高血压患者用动态血压监测仪(ABP)记录血压变化,根据24h平均脉压测定值分为≥60 mm Hg(1 mm Hg=0.133kPa)和<60 mm Hg两组。采用彩色多普勒超声心动图测量左室收缩末径(LVSD)、左室舒张末径(LVDD),室间隔厚度(IVS),左室后壁厚度(LVP),左室射血分数(LVEF)。结果ABPP≥60 mm Hg组LVSD、LVDD、IVS、LVP值明显高于ABPP<60 mm Hg组,而EF低于ABPP<60 mm Hg(P<0.01)。结论老年高血压患者脉压增大与左心室肥厚呈正相关,易于发生心力衰竭,对指导临床血压调整,防止终点事件有一定意义。
Objective To investigate the relationship between mean pulse pressure (ABPP) and left ventricular hypertrophy in elderly patients with hypertension. Methods The changes of blood pressure were recorded in 180 elderly hypertensive patients by using ABP. According to 24h mean pulse pressure, the patients were divided into two groups: ≥60 mm Hg (1 mm Hg = 0.133 kPa) and <60 mm Hg. Left ventricular end systolic diameter (LVSD), left ventricular diastolic diameter (LVDD), interventricular septum thickness (IVS), left ventricular posterior wall thickness (LVP), left ventricular ejection fraction (LVEF ). Results The values of LVSD, LVDD, IVS and LVP in ABPP≥60 mm Hg group were significantly higher than those in ABPP <60 mm Hg group, while EF were lower than ABPP <60 mm Hg group (P <0.01). Conclusions The increase of pulse pressure in elderly hypertensive patients is positively correlated with left ventricular hypertrophy, which is prone to heart failure. It is of some significance to guide clinical blood pressure adjustment and prevent end point events.