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孔雀石绿是一种合成的三苯基甲烷类工业染料,在水产养殖业中用作杀虫剂和预防水霉剂,在生物体内代谢还原成无色孔雀石绿。由于孔雀石绿和无色孔雀石绿潜在的致突变、致畸和致癌危险性,许多国家均禁止其作为人类食用鱼的兽药使用。由于近来在英国市场出售的鲑鱼体内检出孔雀石绿,因此孔雀石绿对健康的危害最近又颇受关注。本文就孔雀石绿的化学性质、代谢和毒性的研究进展进行综述。
Malachite green is a synthetic triphenylmethane industrial dye, used as an insecticide in the aquaculture industry and water-fungicide, metabolically reduced to colorless malachite green in the body. Due to the potential mutagenic, teratogenic and carcinogenic risks of malachite green and malachite green, many countries prohibit their use as veterinary drugs for human consumption of fish. Due to the recent detection of malachite green in salmon that is sold in the UK market, the health hazard of malachite green has drawn some attention lately. This article reviews the research progress of the chemical properties, metabolism and toxicity of malachite green.