1979～1982年,用糖皮质激素治疗慢性活动性肝炎9例,全部临床治愈;治疗重型肝炎19例,有12例显著好转,有效率达63.2％。在尚无特效疗法的情况下,这一疗效是满意的。根据初步观察,糖皮质激素发挥疗效的机制可能同调节肝细胞的生理功能有关,而难以用其抗炎作用和免疫抑制作用进行解释。 From 1979 to 1982, 9 cases of chronic active hepatitis were treated with glucocorticoids, all of which were cured. Treatment of severe hepatitis in 19 cases, 12 cases improved significantly, the effective rate was 63.2%. In the absence of effective therapies, this effect is satisfactory. According to preliminary observations, glucocorticoid efficacy mechanism may be related to the regulation of the physiological function of liver cells, and difficult to explain its anti-inflammatory effects and immunosuppressive effects.