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目的探讨环磷腺苷葡胺和低分子肝素治疗肺源性心脏病急性加重期治疗效果。方法将67例肺源性心脏病急性加重期患者随机分成2组,对照组(33例)给予吸氧、抗生素、平喘、扩血管及利尿等常规治疗;治疗组(34例)在常规治疗的基础上加用环磷腺苷葡胺120mg加入5%葡萄糖溶液250ml静脉滴注,1次/d;低分子肝素2500U,皮下注射,12h/次。疗程共7d。治疗前后进行心功能分级评估、血气分析和心脏超声检查。结果治疗组患者心功能、血气分析和各项心脏指数较对照组改善更为显著(P<0.01)。结论环磷腺苷葡胺和低分子肝素对急性加重期肺源性心脏病患者疗效显著。
Objective To investigate the therapeutic effect of cyclic adenosine monophosphate and low molecular weight heparin in the treatment of acute exacerbation of pulmonary heart disease. Methods Sixty-seven patients with acute exacerbation of pulmonary heart disease were randomly divided into two groups. The control group (33 cases) were given conventional therapy such as oxygen inhalation, antibiotics, asthma, vasodilatation and diuresis. The treatment group (34 cases) Based on the addition of cyclophosphamide meglumine 120mg added 5% glucose solution 250ml intravenous infusion, 1 / d; low molecular weight heparin 2500U, subcutaneous injection, 12h / time. A total of 7d. Heart function before and after treatment grading assessment, blood gas analysis and cardiac ultrasound. Results The cardiac function, blood gas analysis and various cardiac indexes of the treatment group improved more significantly than the control group (P <0.01). Conclusions CAMP and LMWH have a significant effect on patients with acute exacerbation of pulmonary heart disease.